Jamie L. Rogers, Liela Bayeh, et al.Development of Inhibitors of the PAS-B Domain of the HIF-2α Transcription Factor
Hongli Bao, Xiangbing Qi, and Uttam K. TambarCatalytic Enantioselective [2,3]-Rearrangements of Amine N-Oxides
Arash Soheili and Uttam K. TambarTandem Catalytic Allylic Amination and [2,3]-Stevens Rearrangement of Tertiary Amines
Hongli Bao and Uttam TambarCatalytic Enantioselective Allylic Amination of Unactivated Terminal Olefins via an Ene Reaction/[2,3]-Rearrangement
Xiangbing Qi, Hongli Bao, and Uttam K. TambarTotal Synthesis of (±)-Trigonoliimine C via Oxidative Rearrangement of an Unsymmetrical Bis-Tryptamine
The Tambar Group is developing new strategies and concepts in synthetic chemistry to address some of the most challenging problems in our field. Our chemical discoveries will be applied to the synthesis of complex biologically active natural products and their unnatural analogs. In addition to making fundamental advances in the areas of total synthesis and reaction discovery, we are taking advantage of the unique opportunities in medicinal chemistry at UT Southwestern Medical Center.